Pharmacodynamics ntawm Chloroxylenol

Chloroxylenol, los yog para-chloro-meta-xylenol (PCMX), yog ib qho tshuaj tua kab mob thiab ua kom tsis muaj menyuam.Nws yog tus neeg saib xyuas siv hauv tsev kho mob ua yeeb yam los ntxuav cov khoom siv phais.

Chloroxylenol yog ib qho ntawm cov khoom xyaw nquag siv los ua cov tshuaj tua kab mob.Tsis tas li ntawd, nws cov ntawv thov txiav thoob plaws kev kho mob thiab hauv tsev ua tshuaj tua kab mob.

Raws li World Health Organization's List of Essential Medicines, chloroxylenol susceptibility tiv thaiv kab mob hu ua Gram-positive, tau sau tseg zoo.

Txawm li cas los xij, koj puas xav tau cov tshuaj tua kab mob zoo thiab tshuaj tua kab mob rau koj tsev neeg thiab tsev kho mob xav tau, ces koj yuav tsum hu rau tus kws tshaj lij.chloroxylenolneeg tsim khoom.

Pharmacological Indication ntawm Chloroxylenol

Cov ntawv thov chloroxylenol tau hais tau zoo hauv kev kho mob.

Yav dhau los nws tau siv los kho cov kab mob ntawm daim tawv nqaij xws li khawb, txiav, tsiaj tom, stings, thiab tshuaj ntxuav tes.

Pharmacodynamics ntawm Chloroxylenol

Chloroxylenolyog ib qho kev hloov phenol, txhais tau tias nws muaj ib pawg hydroxyl hauv nws cov qauv.

Nws daim ntawv thov tau paub zoo nyob rau xyoo dhau los ua ib qho ntawm cov khoom siv tua kab mob.Nws daim ntawv thov yog npaj sab nraum lub cell.

Nws cov tshuaj tiv thaiv kab mob ntawm me me rau ib pawg kab mob tau tshaj tawm.

Mechanism ntawm Action

Lub xub ntiag ntawm hydroxyl pawg hauv nws cov qauv yog qhov tseem ceeb, tshwj xeeb tshaj yog thaum nws cov peev txheej pharmacological yuav tsum tau piav qhia.

Cov pab pawg hydroxyl yog xav tias yuav txuas mus rau cov protein ntau qhov chaw, uas yog, nyob rau hauv lem, pab nyob rau hauv inhibition ntawm cov kab mob uas nws tawm tsam.

Chloroxylenol nkag mus rau hauv cov kab mob cell mus tua ntau nrog txaus enzymes thiab proteins.Thaum qhov no ua tiav, nws deactivates cov haujlwm ntawm tes.

Nws yuav tau mus rau ib theem uas muaj ntau npaum li cas ntawm Chloroxylenol yog siv rau cov hlab ntsha uas ua rau lawv tuag.

Metabolism ntawm Chloroxylenol

Rau cov ntaub ntawv tsim nyog ntawm Chloroxylenol ua cov kab mob thiab cov tshuaj tua kab mob, cov tsiaj tau siv los kawm tag nrho cov haujlwm ntawm nws cov peev xwm.

Kev ntsuam xyuas tsiaj pom tau tias vim yog siv cov tshuaj chloroxylenol dermal, tus nqi ntawm immersion tau nrawm heev hauv thawj ob teev.

Nws kuj tau pom tias cov tshuaj uas muab rau cov tsiaj tau tso zis tawm hauv lub raum nrog kev tshem tawm tag nrho ntawm qhov nrawm ntawm 24 teev.

Cov khoom tseem ceeb uas tau txheeb xyuas hauv cov qauv defecation suav nrog glucuronides thiab sulfates.

Feem ntau ntawm cov ntawv tshawb fawb txog Chloroxylenol piv nws cov haujlwm rau cov neeg paub zoo thiab muaj kev tiv thaiv kab mob hu ua triclosan.Daim ntawv tshaj tawm tau qhia tias glucuronides kuj yog ib feem ntawm cov qauv defecation hauv tib neeg tus qauv.

Ntau li ntawd, los ntawm tib neeg txoj kev tshawb fawb, nws tau xav tias txhua 5 mg coj mus rau hauv lub cev tom qab ntawd tso zis mus txog 14% ntawm glucuronic acid thiab sulfuric acid hauv peb hnub.

Txawm li cas los xij, ib qho nyiaj ntawm Chloroxylenol coj mus rau hauv lub cev yuav tom qab zom los ntawm daim siab thiab tso zis tawm raws li sulfate thiab glucuronic derivatives.

Txoj Kev Tshem Tawm

Raws li tuaj yeem pom saum toj no los ntawm kev tshawb fawb ua nrog Chloroxylenol qhia tau hais tias txoj hauv kev tseem ceeb chloroxylenol raug tshem tawm ntawm lub cev tom qab kev tswj hwm yog los ntawm cov zis.

Txawm li cas los xij, ib qho me me yog suav tias yog nyob rau hauv cov kua tsib thiab tsawg heev hauv cov pa ua pa.

Koj puas xav tau Chloroxylenol?

Ua siab zoonias ntawm nohnub no rauChloroxylenolrau tag nrho koj cov khoom siv tshuaj tua kab mob thiab tshuaj tua kab mob, thiab peb yuav zoo siab koom tes nrog koj rau cov khoom zoo tshaj plaws.