Ua ib qho saturated ncaj-saw aliphatic dibasic aldehyde, glutaraldehyde yog ib qho kua tsis muaj xim pob tshab nrog ntxhiab tsw khaus thiab tua tau zoo heev rau cov kab mob reproductive, cov kab mob, mycobacteria, pwm pathogenic thiab cov kab mob bacterial, thiab cov kab mob bacterial broad-spectrum non-oxidizing. Glutaraldehyde yog ib qho tshuaj tua kab mob zoo heev uas tua ntau yam kab mob me me thiab tau pom zoo los ntawm World Health Organization ua tshuaj tua kab mob rau cov kab mob hepatitis.
Glutaraldehyde 25%muaj cov teebmeem txhawb thiab kho rau tib neeg daim tawv nqaij thiab cov ntaub so ntswg thiab tej zaum yuav ua rau ua xua, yog li nws yuav tsum tsis txhob siv rau kev tua kab mob ntawm huab cua thiab cov khoom siv noj mov. Tsis tas li ntawd, glutaraldehyde yuav tsum tsis txhob siv rau kev tua kab mob thiab kev tua kab mob ntawm cov khoom siv kho mob tubular, koob txhaj tshuaj, cov xov phais thiab cov xov paj rwb.
Glutaraldehyde feem ntau siv ua tshuaj tua kab mob hauv kev lag luam kho mob thiab cov neeg siv yuav muaj lus nug txog cov teeb meem kev siv tshuab, yog li Springchem ntawm no muab cov ntsiab lus tseem ceeb txog glutaraldehyde rau koj siv.
Akev siv glutaraldehyde
Glutaraldehyde siv ua tshuaj tua kab mob txias los tua cov cuab yeej rhiab heev rau qhov kub, xws li endoscopes thiab cov khoom siv dialysis. Nws yog siv ua tshuaj tua kab mob siab rau cov cuab yeej phais uas tsis tuaj yeem tua kab mob kub.
Glutaraldehyde siv rau ntau daim ntawv thov hauv cov chaw kho mob:
● Ib yam khoom siv kho cov nqaij hauv chav kuaj mob
● Tshuaj tua kab mob thiab tshuaj tua kab mob ntawm cov chaw thiab cov khoom siv
● Ib yam khoom siv los ua kom tawv tawv siv los tsim cov duab X-ray
● Rau kev npaj cov noob cog
Lub sijhawm tas sij hawmhnub tim ntawm glutaraldehyde thiab yuav ua li cas txiav txim siab lub sijhawm tas sij hawm
Nyob rau hauv chav tsev kub thiab nyob rau hauv qhov xwm txheej ntawm kev nyob deb ntawm lub teeb thiab kaw cia, hnub tas sij hawm ntawm glutaraldehyde yuav tsum tsis pub tsawg dua 2 xyoos, thiab cov khoom xyaw nquag ntawm glutaraldehyde yuav tsum muaj tsawg kawg yog 2.0% hauv hnub tas sij hawm.
Thaum sov li chav tsev, tom qab ntxiv cov tshuaj tiv thaiv xeb thiab cov tshuaj kho pH, glutaraldehyde siv rau kev tua kab mob lossis ua kom tsis muaj menyuam hauv cov khoom siv kho mob, thiab siv tau 14 hnub txuas ntxiv. Cov ntsiab lus glutaraldehyde yuav tsum muaj tsawg kawg yog 1.8% thaum siv.
Kev Kawm Txog Kev Nkag Mus Rau Hauv Dejdkev kis kab mobtxoj kevnrog glutaraldehyde
Muab cov cuab yeej uas tau ntxuav lawm tso rau hauv 2.0% ~ 2.5% glutaraldehyde disinfection solution kom nws nyob hauv dej tag nrho, ces muab npog lub thawv tua kab mob rau ntawm chav tsev kub li 60 feeb, thiab yaug nrog dej huv ua ntej siv.
Cov cuab yeej kuaj mob thiab kho mob, cov khoom siv, thiab cov khoom siv uas tau ntxuav thiab ziab lawm, muab tso rau hauv 2% alkaline glutaraldehyde kua uas nyob hauv qab dej tag, thiab cov pa npuas ntawm qhov chaw ntawm cov cuab yeej yuav tsum tau muab tshem tawm nrog lub thawv uas npog ntawm qhov kub ntawm 20 ~ 25 ℃. Kev tua kab mob ua haujlwm kom txog thaum lub sijhawm teev tseg ntawm cov lus qhia ntawm cov khoom.
Cov kev cai rau kev tua kab mob ntawm endoscopes nrog glutaraldehyde
1. Cov txheej txheem tua kab mob thiab kev ua kom tsis muaj menyuam siab
● Kev Ntsuas: ≥2% (alkaline)
● Lub Sijhawm: lub sijhawm siv tshuaj tua kab mob los ntawm kev siv lub tshuab tsom iav ≥ 20 feeb; lwm yam kev siv tshuab tsom iav tua kab mob ≥ 10 feeb; kev siv lub tshuab tsom iav rau cov neeg mob uas muaj tus kab mob mycobacterium tuberculosis, lwm yam kab mob mycobacteria thiab lwm yam kab mob tshwj xeeb ≥ 45 feeb; kev tua kab mob ≥ 10 teev
2. Siv txoj kev
● Tshuab ntxuav thiab tua kab mob Endoscope
● Kev siv tes: yuav tsum muab tshuaj tua kab mob ntim rau hauv txhua lub yeeb nkab thiab muab dej ntub kom tua kab mob
3. Kev ceev faj
Glutaraldehyde 25%ua rau ua xua thiab khaus rau daim tawv nqaij, qhov muag thiab ua pa, thiab tuaj yeem ua rau mob dermatitis, conjunctivitis, qhov ntswg o thiab mob hawb pob ua haujlwm, yog li nws yuav tsum tau siv rau hauv kev ntxuav thiab tua kab mob endoscope.
Kev ceev faj nrog glutaraldehyde
Glutaraldehyde ua rau khaus tawv nqaij thiab cov ntaub so ntswg thiab lom rau tib neeg, thiab cov kua glutaraldehyde tuaj yeem ua rau lub qhov muag puas tsuaj loj heev. Yog li ntawd, nws yuav tsum tau npaj thiab siv rau hauv qhov chaw uas muaj cua nkag zoo, kev tiv thaiv tus kheej yuav tsum tau npaj zoo, xws li hnav lub ntsej muag tiv thaiv, hnab looj tes tiv thaiv thiab tsom iav tiv thaiv. Yog tias raug kov tsis raug, nws yuav tsum tau yaug tam sim ntawd thiab txuas ntxiv nrog dej, thiab yuav tsum tau nrhiav kev kho mob thaum ntxov yog tias lub qhov muag raug mob.
Yuav tsum siv rau qhov chaw uas muaj cua nkag tau zoo, thiab yog tias tsim nyog, qhov chaw ntawd yuav tsum muaj cov khoom siv tso pa tawm. Yog tias qhov concentration ntawm glutaraldehyde hauv huab cua ntawm qhov chaw siv siab dhau, nws raug pom zoo kom nruab nrog cov khoom siv ua pa uas muaj peev xwm ua pa tau (lub ntsej muag tiv thaiv siab zoo). Cov thawv uas siv rau cov cuab yeej ntub dej yuav tsum huv, npog thiab tua kab mob ua ntej siv.
Kev saib xyuas zaus ntawm glutaraldehyde concentration
Qhov concentration ntawm glutaraldehyde zoo tuaj yeem saib xyuas nrog cov ntawv xeem tshuaj lom neeg.
Thaum siv tas li, yuav tsum tau saib xyuas txhua hnub kom nkag siab txog nws cov kev hloov pauv ntawm cov tshuaj, thiab yuav tsum tsis txhob siv thaum nws cov tshuaj pom tias qis dua qhov xav tau.
Yuav tsum xyuas kom meej tias qhov concentration ntawm glutaraldehyde siv ua tau raws li qhov yuav tsum tau ua ntawm phau ntawv qhia khoom.
Yuav tsumglutaraldehyde yuav tsum tau qhib ua ntej siv?
Cov kua dej ntawm glutaraldehyde yog acidic thiab feem ntau tsis tuaj yeem tua cov noob tawg hauv lub xeev acidic. Tsuas yog thaum cov kua raug "activated" los ntawm alkalinity mus rau pH tus nqi ntawm 7.5-8.5 uas nws tuaj yeem tua cov noob. Thaum ua haujlwm, cov kua no muaj lub sijhawm khaws cia tsawg kawg yog 14 hnub. Ntawm cov pH alkaline, cov molecules glutaraldehyde feem ntau polymerize. Kev polymerization ntawm glutaraldehyde ua rau kaw ntawm qhov chaw aldehyde pawg ntawm nws cov molecule glutaraldehyde uas yog lub luag haujlwm rau tua cov noob tawg, thiab yog li ntawd cov nyhuv bactericidal txo qis.
Cov yam tseem ceeb uas cuam tshuam rau kev ua kom tsis muaj menyuam ntawm glutaraldehyde
1. Lub sijhawm tsom ntsoov thiab lub sijhawm ua haujlwm
Qhov kev tua kab mob yuav raug txhim kho nrog kev nce ntxiv ntawm qhov concentration thiab lub sijhawm ua haujlwm ntev. Txawm li cas los xij, cov tshuaj glutaraldehyde nrog qhov feem pua ntawm qhov hnyav tsawg dua 2% tsis tuaj yeem ua tiav qhov kev tua kab mob ntawm cov kab mob, txawm tias yuav ua li cas thiaj li ncua lub sijhawm tua kab mob. Yog li ntawd, nws yog qhov tsim nyog siv cov tshuaj glutaraldehyde nrog qhov feem pua ntau dua 2% los tua cov kab mob.
2. Cov kua qaub thiab alkalinity ntawm cov tshuaj
Cov nyhuv tua kab mob ntawm cov kua qaub glutaraldehyde qis dua li ntawm alkaline glutaraldehyde, tab sis qhov sib txawv yuav maj mam txo qis nrog qhov kub nce. Hauv qhov ntau ntawm pH 4.0-9.0, cov nyhuv tua kab mob nce ntxiv nrog pH nce; cov nyhuv tua kab mob muaj zog tshaj plaws pom ntawm pH 7.5-8.5; ntawm pH > 9, glutaraldehyde polymerizes sai sai thiab cov nyhuv tua kab mob ploj sai.
3. Kub
Nws kuj muaj cov nyhuv tua kab mob ntawm qhov kub qis dua. Cov nyhuv tua kab mob ntawm glutaraldehyde nce nrog rau qhov kub thiab txias, thiab nws cov coefficient kub (Q10) yog 1.5 txog 4.0 ntawm 20-60 ℃.
4. Cov khoom siv organic
Cov khoom siv organic ua rau cov nyhuv bactericidal tsis muaj zog, tab sis cov nyhuv ntawm cov khoom siv organic rau cov nyhuv bactericidal ntawm glutaraldehyde yog me dua li ntawm lwm cov tshuaj tua kab mob. 20% calf serum thiab 1% tag nrho cov ntshav yeej tsis muaj cov nyhuv rau cov nyhuv bactericidal ntawm 2% glutaraldehyde.
5. Cov nyhuv synergistic ntawm nonionic surfactants thiab lwm yam physicochemical yam
Polyoxyethylene fatty alcohol ether yog ib qho surfactant nonionic, thiab qhov ruaj khov thiab cov nyhuv bactericidal tau zoo dua los ntawm kev ntxiv 0.25% polyoxyethylene fatty alcohol ether rau hauv glutaraldehyde kua uas tsim nrog cov kua qaub-base glutaraldehyde. Ultrasound, cov duab infrared deb thiab glutaraldehyde muaj cov nyhuv synergistic sterilization.
Springchem, yog ib lub tuam txhab tsim khoom glutaraldehyde 10 lub npe nrov hauv Suav teb, muab glutaraldehyde 25% thiab 50% rau kev lag luam, chaw kuaj mob, kev ua liaj ua teb, kev kho mob, thiab qee yam hauv tsev neeg, feem ntau yog rau kev tua kab mob thiab ua kom huv ntawm cov chaw thiab cov khoom siv. Yog xav paub ntxiv, hu rau peb.
Lub sijhawm tshaj tawm: Lub Yim Hli-16-2022