Hauv qab no yog cov lus qhia luv luv txog cov txheej txheem kev ua haujlwm, hom nrog rau kev ntsuas ntsuas ntawm ntau yam tshuaj tiv thaiv
1.Zuag qhia tag nrho hom kev ua ntawmtshuaj khaws cia
Preservative yog cov tshuaj lom neeg ua haujlwm tseem ceeb uas pab tua lossis cuam tshuam cov haujlwm ntawm cov kab mob hauv cov tshuaj pleev ib ce nrog rau kev tswj xyuas tag nrho cov tshuaj pleev ib ce zoo nyob rau lub sijhawm ntev.
Txawm li cas los xij, nws yuav tsum tau muab sau tseg tias cov tshuaj tua kab mob tsis yog tshuaj tua kab mob 鈥 lawv tsis muaj cov kab mob bactericidal muaj zog, thiab lawv tsuas yog ua haujlwm thaum siv kom muaj nuj nqis txaus lossis thaum lawv muaj kev sib cuag nrog cov kab mob.
Preservatives inhibit microbial kev loj hlob yuav thaiv cov synthesis ntawm tseem ceeb metabolic enzymes nrog rau inhibiting synthesis ntawm cov proteins nyob rau hauv tseem ceeb cell Cheebtsam los yog cov synthesis ntawm nucleic acid.
2.Cov yam ntxwv cuam tshuam rau Kev Ua Haujlwm ntawm Kev Tiv Thaiv
Muaj ntau yam ua rau cov nyhuv ntawm preservatives.Lawv suav nrog;
a.Qhov cuam tshuam ntawm pH
Ib qho kev hloov pauv hauv pH ua rau muaj kev cuam tshuam ntawm cov organic acid preservatives, thiab yog li cuam tshuam rau tag nrho cov kev ua tau zoo ntawm preservatives.Piv txwv li, ntawm pH 4 thiab pH 6, 2-bromo-2-nitro-1,3-propanediol yog qhov ruaj khov heev
b.Cov teebmeem ntawm cov gel thiab cov khoom ua haujlwm
Koalin, magnesium silicate, txhuas thiab lwm yam, yog qee cov hmoov hmoov uas muaj nyob rau hauv qee cov tshuaj pleev ib ce, uas feem ntau nqus cov khoom noj thiab yog li ua rau poob ntawm kev ua haujlwm los ntawm kev khaws cia.Txawm li cas los xij, qee qhov kuj tseem muaj txiaj ntsig zoo hauv kev nqus cov kab mob uas muaj nyob hauv cov tshuaj tiv thaiv.Tsis tas li ntawd, kev sib xyaw ua ke ntawm cov dej-soluble polymer gel thiab preservative pab txo qis concentration ntawm residual preservative nyob rau hauv cov tshuaj pleev ib ce formulation, thiab qhov no kuj txo cov nyhuv ntawm preservative.
c.Solubilization nyhuv ntawm nonionic surfactants
Lub solubilization ntawm ntau yam surfactants xws li nonionic surfactants nyob rau hauv preservatives kuj muaj feem xyuam rau tag nrho cov kev ua ntawm preservatives.Txawm li cas los xij, roj-soluble nonionic surfactants xws li HLB = 3-6 paub tias muaj peev xwm deactivation ntau dua ntawm cov khoom khaws cia piv rau cov dej soluble nonionic surfactants nrog tus nqi siab dua HLB.
d.Cov nyhuv ntawm preservative deterioration
Muaj lwm yam xws li cua sov, lub teeb thiab lwm yam, uas yog lub luag hauj lwm ua rau deterioration ntawm preservatives, yog li ua rau ib tug txo nyob rau hauv lawv antiseptic nyhuv.Tsis tas li ntawd, qee qhov kev cuam tshuam no ua rau muaj cov tshuaj tiv thaiv biochemical raws li qhov tshwm sim ntawm hluav taws xob kom tsis muaj menyuam thiab tshuaj tua kab mob.
e.Lwm cov haujlwm
Ib yam li ntawd, lwm yam xws li muaj cov tsw qab thiab cov neeg ua haujlwm chelating thiab kev faib cov tshuaj tua kab mob hauv cov roj-dej ob-theem kuj tseem yuav ua rau txo qis hauv kev ua haujlwm ntawm cov tshuaj tua kab mob rau qee qhov.
3.Antiseptic thaj chaw ntawm preservatives
Antiseptic thaj chaw ntawm preservatives yog tsim nyog xav txog.Muaj ntau preservatives nyob rau hauv cov tshuaj pleev ib ce yuav twv yuav raug hu ua rau nws irritating, thaum lub shortage ntawm concentration yuav cuam tshuam rau cov tshuaj tua kab mob.cov khoom ntawm preservatives.Txoj hauv kev zoo tshaj plaws los ntsuas qhov no yog siv cov kev sim tshuaj lom neeg uas cuam tshuam nrog qhov tsawg kawg nkaus inhibitory concentration (MIC) thiab qhov ntsuas qhov chaw tiv thaiv.
Bacteriostatic vajvoog test: Qhov kev ntsuam xyuas no yog siv los txiav txim cov kab mob thiab pwm nrog lub peev xwm loj hlob sai heev tom qab cog rau ntawm qhov nruab nrab tsim nyog.Nyob rau hauv ib qho teeb meem uas ib daim ntawv lim impregnated nrog preservative poob rau hauv nruab nrab ntawm cov kab lis kev cai nruab nrab phaj, yuav muaj ib tug bacteriostatic vajvoog tsim nyob ib ncig ntawm vim yog nkag mus rau cov preservative.Thaum ntsuas txoj kab uas hla ntawm lub voj voog bacteriostatic, nws tuaj yeem siv los ua ib lub yardstick los txiav txim seb qhov ua tau zoo ntawm kev khaws cia.
Nrog rau qhov no, nws tuaj yeem hais tias lub voj voog kab mob bacteriostatic siv daim ntawv txoj kab uas hla > = 1.0mm yog qhov zoo heev.MIC yog hu ua qhov tsawg tshaj plaws concentration ntawm preservative uas yuav muab ntxiv rau hauv nruab nrab los inhibit microbial kev loj hlob.Nyob rau hauv cov xwm txheej zoo li no, ib qho me me MIC, qhov muaj zog ntawm cov tshuaj tua kab mob ntawm cov tshuaj tua kab mob.
Lub zog lossis cov nyhuv ntawm cov tshuaj tiv thaiv kab mob feem ntau yog qhia nyob rau hauv daim ntawv ntawm qhov tsawg kawg nkaus inhibitory concentration (MIC).Los ntawm kev ua li ntawd, kev ua kom muaj zog tiv thaiv kab mob yog txiav txim los ntawm tus nqi me me ntawm MIC.Txawm hais tias MIC tsis tuaj yeem siv los sib txawv ntawm cov kab mob bactericidal thiab bacteriostatic, surfactants feem ntau paub tias muaj cov nyhuv bacteriostatic ntawm qhov tsis tshua muaj siab thiab ua kom tsis muaj menyuam ntawm qhov siab.
Raws li qhov tseeb, nyob rau lub sijhawm sib txawv, ob txoj haujlwm no tshwm sim tib lub sijhawm, thiab qhov no ua rau lawv nyuaj rau kev sib txawv.Vim li no, lawv feem ntau tau muab lub npe sau ua tshuaj tua kab mob los yog tshuaj tua kab mob yooj yim.
Post lub sij hawm: Jun-10-2021