Arbutinyog ib qho tshwm sim tshwm sim nyob rau hauv ntau yam nroj tsuag xws li bearberry, cranberries, thiab blueberries.Nws tau txais kev saib xyuas tseem ceeb hauv kev kho tawv nqaij thiab kev lag luam tshuaj pleev ib ce vim nws cov peev xwm ntawm daim tawv nqaij whitening thiab lightening zog.Cov txheej txheem tom qab cov teebmeem dawb ntawm arbutin yog nyob ib puag ncig nws lub peev xwm los cuam tshuam cov haujlwm ntawm cov enzyme hu ua tyrosinase, uas ua lub luag haujlwm tseem ceeb hauv kev tsim cov melanin - cov xim ua lub luag haujlwm rau daim tawv nqaij, plaub hau, thiab qhov muag xim.
Cov tawv nqaij xim yog txiav txim siab los ntawm tus nqi thiab kev faib tawm ntawm melanin tsim los ntawm melanocytes, cov hlwb tshwj xeeb hauv cov txheej txheem epidermal.Tyrosinase yog ib qho tseem ceeb enzyme nyob rau hauv melanin synthesis txoj kev, catalyzing hloov dua siab tshiab ntawm cov amino acid tyrosine rau melanin precursors, uas nws thiaj li ua rau tsim ntawm melanin pigments.Arbutin exerts nws cov nyhuv whitening feem ntau los ntawm kev sib tw inhibition ntawm tyrosinase kev ua.
Arbutin muaj glycoside daim ntawv cog lus, uas yog cov tshuaj sib txuas ntawm cov piam thaj molecule thiab hydroquinone molecule.Hydroquinone yog ib qho kev paub zoo nrog cov khoom siv tawv nqaij, tab sis nws tuaj yeem ua rau tawv nqaij hnyav thiab cuam tshuam nrog cov kev mob tshwm sim.Arbutin, ntawm qhov tod tes, ua raws li kev hloov pauv hloov mus rau hydroquinone thaum tseem muab cov txiaj ntsig zoo melanin inhibition.
Thaum arbutin siv rau ntawm daim tawv nqaij, nws yog absorbed thiab metabolized rau hauv hydroquinone los ntawm cov txheej txheem enzymatic.Qhov no hydroquinone ces sib tw inhibits qhov kev txiav txim ntawm tyrosinase los ntawm occupying nws active site.Yog li ntawd, tyrosine molecules tsis tuaj yeem hloov mus rau hauv melanin precursors, ua rau txo qis ntawm melanin.Qhov no thaum kawg ua rau kev txo qis ntawm daim tawv nqaij pigmentation, ua rau lub cev sib dua thiab ntau dua cov tawv nqaij.
Nws yog ib qho tseem ceeb kom nco ntsoov tiasarbutin's whiteningcov teebmeem tsis yog tam sim ntawd.Kev hloov pauv ntawm daim tawv nqaij yuav siv sijhawm li ib hlis, yog li kev siv cov khoom uas muaj arbutin ntev ntev yog qhov tsim nyog los soj ntsuam cov kev hloov pauv ntawm daim tawv nqaij pigmentation.Tsis tas li ntawd, arbutin cov txheej txheem ntawm kev ua haujlwm zoo dua rau kev daws cov teeb meem ntsig txog hyperpigmentation, xws li hnub nyoog me ntsis, tshav pob, thiab melasma, tsis yog hloov cov xim ntawm daim tawv nqaij.
Arbutin's kev ruaj ntseg profile yog feem ntau zam tau zoo dua li qee cov neeg ua haujlwm ntawm daim tawv nqaij, ua rau nws yog qhov kev xaiv nrov rau cov tib neeg tab tom nrhiav los daws cov tawv nqaij tsis sib xws.Txawm li cas los xij, cov kev xav ntawm tus kheej tuaj yeem sib txawv, thiab nws raug nquahu kom ua qhov ntsuas patch ua ntej muab cov khoom tu tawv nqaij tshiab rau hauv koj lub sijhawm.
Hauv kev xaus, cov txheej txheem ntawm daim tawv nqaij dawb ntawm arbutin tso siab rau nws lub peev xwm los inhibit tyrosinase kev ua, ua rau txo qis melanin ntau lawm.Nws qhov kev sib tw inhibition ntawm tyrosinase, ua rau txo qis melanin synthesis, ua rau nws muaj txiaj ntsig zoo hauv cov khoom tu tawv nqaij tsom hyperpigmentation thiab cov tawv nqaij tsis sib xws.Raws li nrog rau txhua yam khoom siv tu tawv nqaij, nws raug nquahu kom sab laj nrog kws kho mob dermatologist ua ntej qhia cov khoom tshiab rau koj li niaj hnub, tshwj xeeb tshaj yog tias koj muaj kev txhawj xeeb tshwj xeeb ntawm daim tawv nqaij lossis mob.
Post lub sij hawm: Aug-30-2023