Arbutinyog ib qho tshuaj uas muaj nyob rau hauv ntau yam nroj tsuag xws li bearberry, cranberries, thiab blueberries. Nws tau txais kev saib xyuas tseem ceeb hauv kev lag luam saib xyuas tawv nqaij thiab kev lag luam pleev ib ce vim nws muaj peev xwm ua kom tawv nqaij dawb thiab ci ntsa iab. Lub tshuab tom qab cov teebmeem dawb ntawm arbutin tig ib puag ncig nws lub peev xwm los tiv thaiv kev ua haujlwm ntawm cov enzyme hu ua tyrosinase, uas ua lub luag haujlwm tseem ceeb hauv kev tsim cov melanin - cov xim uas yog lub luag haujlwm rau tawv nqaij, plaub hau, thiab xim qhov muag.
Xim ntawm daim tawv nqaij yog txiav txim siab los ntawm qhov ntau thiab kev faib tawm ntawm melanin uas tsim los ntawm melanocytes, cov hlwb tshwj xeeb hauv txheej epidermal. Tyrosinase yog ib qho enzyme tseem ceeb hauv txoj kev tsim melanin, catalyzing qhov kev hloov pauv ntawm cov amino acid tyrosine mus rau hauv melanin precursors, uas thaum kawg ua rau muaj cov xim melanin. Arbutin ua rau nws cov nyhuv dawb feem ntau los ntawm kev sib tw inhibition ntawm tyrosinase kev ua ub no.
Arbutin muaj ib qho glycoside bond, uas yog ib qho kev sib txuas ntawm cov glucose molecule thiab hydroquinone molecule. Hydroquinone yog ib qho tshuaj uas paub zoo tias muaj cov khoom ua rau daim tawv nqaij dawb, tab sis nws tuaj yeem ua rau daim tawv nqaij hnyav thiab muaj feem cuam tshuam nrog cov kev phiv. Arbutin, ntawm qhov tod tes, ua haujlwm zoo dua li hydroquinone thaum tseem muab kev tiv thaiv kev tsim melanin zoo.
Thaum arbutin siv rau ntawm daim tawv nqaij, nws raug nqus thiab metabolized rau hauv hydroquinone los ntawm cov txheej txheem enzymatic. Cov hydroquinone no ces sib tw tiv thaiv kev ua haujlwm ntawm tyrosinase los ntawm kev nyob hauv nws qhov chaw nquag. Yog li ntawd, tyrosine molecules tsis tuaj yeem hloov pauv mus rau hauv melanin precursors, ua rau txo qis ntawm melanin. Qhov no thaum kawg ua rau maj mam txo qis ntawm cov xim tawv nqaij, ua rau lub ntsej muag sib dua thiab sib npaug dua.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tiasarbutin ua kom dawbCov teebmeem tsis yog tam sim ntawd. Kev hloov pauv ntawm daim tawv nqaij siv sijhawm li ib hlis, yog li kev siv cov khoom muaj arbutin tas li thiab ntev yog qhov tsim nyog los saib xyuas kev hloov pauv ntawm cov xim tawv nqaij. Tsis tas li ntawd, arbutin txoj hauv kev ua haujlwm zoo dua rau kev daws cov teeb meem ntsig txog hyperpigmentation, xws li cov pob hnub nyoog, cov pob hnub, thiab melasma, es tsis yog hloov pauv xim tawv nqaij.
Arbutin txoj kev nyab xeeb feem ntau zoo dua li lwm cov tshuaj pleev kom tawv nqaij dawb, ua rau nws yog ib qho kev xaiv nrov rau cov tib neeg uas tab tom nrhiav kev daws teeb meem tsis sib xws ntawm cov tawv nqaij. Txawm li cas los xij, cov kev xav ntawm tus kheej tuaj yeem sib txawv, thiab nws yog ib qho kev pom zoo kom ua qhov kev sim ua ntej siv cov khoom siv saib xyuas tawv nqaij tshiab rau hauv koj txoj kev niaj hnub.
Xaus lus, lub tshuab ua kom tawv nqaij dawb ntawm arbutin vam khom nws lub peev xwm los tiv thaiv tyrosinase kev ua haujlwm, ua rau txo qis melanin ntau lawm. Nws qhov kev sib tw tiv thaiv tyrosinase, ua rau txo qis melanin synthesis, ua rau nws yog ib qho khoom xyaw zoo hauv cov khoom siv tawv nqaij uas tsom mus rau hyperpigmentation thiab cov xim tawv nqaij tsis sib xws. Ib yam li cov khoom xyaw tawv nqaij, nws raug pom zoo kom sab laj nrog kws kho mob tawv nqaij ua ntej qhia cov khoom tshiab rau koj txoj kev niaj hnub, tshwj xeeb tshaj yog tias koj muaj kev txhawj xeeb lossis mob ntawm daim tawv nqaij.
Lub sijhawm tshaj tawm: Lub Yim Hli-30-2023