Triclosanyog ib qho tshuaj tua kab mob dav dav uas siv los ua tshuaj tua kab mob, tshuaj tua kab mob lossis tshuaj tiv thaiv hauv chaw kho mob, ntau yam khoom siv xws li tshuaj pleev ib ce, khoom siv ntxuav hauv tsev, cov khoom siv yas, cov khoom ua si, xim, thiab lwm yam. Nws kuj tseem siv rau ntawm qhov chaw ntawm cov khoom siv kho mob, cov khoom siv yas, textiles, cov khoom siv hauv chav ua noj, thiab lwm yam, uas nws yuav maj mam leach rau lub sijhawm ntev thaum lawv siv, los ua nws cov kev ua biocidal.
Triclosan siv li cas hauv kev pleev xim?
Triclosantau teev nyob rau hauv xyoo 1986 hauv European Community Cosmetics Directive rau kev siv ua cov tshuaj preservative hauv cov khoom siv pleev kom zoo nkauj ntawm qhov concentration txog li 0.3%. Kev ntsuam xyuas kev pheej hmoo tsis ntev los no ua los ntawm EU Scientific Committee on Consumer Products xaus lus tias, txawm hais tias nws siv ntawm qhov concentration siab tshaj plaws ntawm 0.3% hauv cov tshuaj txhuam hniav, xab npum tes, xab npum lub cev / da dej gels thiab deodorant sticks tau suav tias muaj kev nyab xeeb ntawm qhov pom ntawm kev lom hauv cov khoom ib leeg, qhov loj ntawm kev raug triclosan los ntawm txhua yam khoom siv pleev kom zoo nkauj tsis muaj kev nyab xeeb.
Kev siv triclosan ntxiv rau hauv cov hmoov ntsej muag thiab cov tshuaj pleev thaiv qhov muag ntawm qhov concentration no kuj suav tias muaj kev nyab xeeb, tab sis kev siv triclosan hauv lwm cov khoom siv uas tsis muaj ntawv (piv txwv li cov tshuaj pleev lub cev) thiab hauv cov tshuaj ntxuav qhov ncauj tsis suav tias muaj kev nyab xeeb rau tus neeg siv khoom vim yog qhov ua rau muaj kev phom sij ntau. Kev ua pa ntawm kev raug triclosan los ntawm cov tshuaj tsuag (piv txwv li cov tshuaj deodorants) tsis tau raug soj ntsuam.
TriclosanVim nws tsis yog ionic, nws tuaj yeem tsim tau rau hauv cov tshuaj hniav ib txwm muaj. Txawm li cas los xij, nws tsis khi rau ntawm qhov ncauj ntau tshaj ob peb teev, thiab yog li ntawd nws tsis ua haujlwm tiv thaiv cov quav hniav. Txhawm rau kom nce kev nqus thiab khaws cia ntawm triclosan los ntawm qhov ncauj rau kev txhim kho kev tswj cov quav hniav thiab kev noj qab haus huv ntawm cov pos hniav, triclosan / polyvinylmethyl ether maleic acid copolymer thiab triclosan / zinc citrate thiab triclosan / calcium carbonate dentifrice raug siv.
Triclosan siv li cas hauv kev kho mob thiab cov khoom siv kho mob?
Triclosantau siv tau zoo hauv kev kho mob los tshem tawm cov kab mob me me xws li methicillin-resistant Staphylococcus aureus (MRSA), tshwj xeeb nrog rau kev pom zoo kom siv 2% triclosan da dej. Triclosan siv ua cov tshuaj txhuam phais, thiab nws siv dav hauv kev ntxuav tes thiab ua tshuaj ntxuav lub cev kom tshem tawm MRSA ntawm cov neeg nqa khoom ua ntej phais.
Triclosan siv rau hauv ntau yam khoom siv kho mob, piv txwv li ureteral stents, phais sutures thiab tej zaum yuav raug txiav txim siab los tiv thaiv kev kis kab mob graft. Bojar et al tsis tau pom qhov sib txawv ntawm kev sib sau ua ke ntawm triclosan-coated sutures thiab multifilament suture, txawm hais tias lawv txoj haujlwm txhawj xeeb txog tsib tus kab mob thiab tsuas yog raws li kev txiav txim siab ntawm thaj chaw ntawm kev txwv.
Hauv cov ureteral stents, triclosan tau pom tias tiv thaiv kev loj hlob ntawm cov kab mob uropathogens thiab txo qhov tshwm sim ntawm kev kis kab mob ntawm txoj hlab zis thiab, tej zaum, catheter encrustation tsis ntev los no tau ua pov thawj cov teebmeem synergistic ntawm triclosan thiab cov tshuaj tua kab mob cuam tshuam rau cov chaw kho mob uas muaj xya hom uropathogenic, thiab lawv txhawb nqa kev siv triclosan-eluting stent thaum tsim nyog, nrog rau kev kho mob tshuaj tua kab mob tus qauv hauv kev kho cov neeg mob nyuaj.
Hauv qee qhov kev txhim kho ntxiv, kev siv triclosan hauv cov zis Foley catheter tau raug pom zoo vim tias triclosan tau ua tiav inhibit qhov kev loj hlob ntawm Proteus mirabilis thiab tswj kev encrustation thiab blockage ntawm lub catheter. Tsis ntev los no, Darouiche et al. tau ua pov thawj synergistic, broad-spectrum thiab ruaj khov antimicrobial kev ua haujlwm ntawm cov catheters coated nrog kev sib xyaw ua ke ntawm triclosan thiab DispersinB, ib qho enzyme anti-biofilm uas inhibits thiab disperses biofilms.
Triclosan siv li cas rau lwm cov khoom siv rau cov neeg siv khoom?
Qhov kev ua haujlwm tiv thaiv kab mob dav dav ntawm triclosan tau ua rau nws suav nrog ntau yam khoom tsim rau kev siv hauv tsev xws li xab npum ua kua, tshuaj ntxuav tes, cov laug txiav, cov khoom ua si rau menyuam yaus, cov ntaub pua plag thiab cov thawv cia khoom noj. Daim ntawv teev cov khoom siv rau cov neeg siv khoom uas muaj triclosan yog muab los ntawm US Environmental Protection Agency (EPA) thiab los ntawm US NGOs "Environmental Working Group" thiab "Beyond Pesticides".
Muaj ntau cov khaub ncaws uas siv cov tshuaj tua kab mob los kho. Triclosan yog ib qho ntawm cov tshuaj ua tiav rau kev tsim cov ntaub zoo li no. Cov ntaub uas siv triclosan los kho cov tshuaj sib txuas kom muaj zog tiv thaiv kab mob. Raws li cov ntaub ntawv muaj, 17 yam khoom los ntawm kev lag luam muag khoom hauv Danish tau raug tshuaj xyuas seb puas muaj cov tshuaj tua kab mob hauv cov ntaub: triclosan, dichlorophen, Kathon 893, hexachlorophen, triclocarban thiab Kathon CG. Tsib yam khoom muaj 0.0007% - 0.0195% triclosan.
Aiello et al hauv thawj qhov kev tshuaj xyuas tsis tu ncua uas ntsuas qhov txiaj ntsig ntawm cov xab npum uas muaj triclosan, tau soj ntsuam 27 txoj kev tshawb fawb luam tawm ntawm xyoo 1980 thiab 2006. Ib qho ntawm cov ntsiab lus tseem ceeb yog tias cov xab npum uas muaj tsawg dua 1% triclosan tsis muaj txiaj ntsig los ntawm cov xab npum uas tsis yog tshuaj tua kab mob. Cov kev tshawb fawb uas siv xab npum uas muaj > 1% triclosan tau qhia txog kev txo qis ntawm cov kab mob hauv tes, feem ntau tom qab siv ntau zaus.
Qhov tsis muaj kev sib raug zoo ntawm kev siv xab npum uas muaj triclosan thiab kev txo qis ntawm kev kis kab mob nyuaj rau paub tseeb tias tsis muaj kev txheeb xyuas cov kab mob uas ua rau muaj cov tsos mob ntawm tus kab mob. Ob txoj kev tshawb fawb tsis ntev los no hauv Tebchaws Meskas tau qhia tias kev ntxuav tes nrog xab npum tua kab mob uas muaj triclosan (0.46%) txo cov kab mob thiab kev kis kab mob ntawm tes, piv rau kev ntxuav tes nrog xab npum uas tsis muaj tshuaj tua kab mob.
Cov Khoom Siv Caij Nplooj Ntoos Hlav
Peb tsim ntau yam khoom uas siv tau rau hauv kev saib xyuas tus kheej thiab kev lag luam pleev kom zoo nkauj, xws li kev saib xyuas tawv nqaij, kev saib xyuas plaub hau, kev saib xyuas qhov ncauj, tshuaj pleev kom zoo nkauj, kev ntxuav tsev neeg, kev ntxuav xab npum thiab ntxhua khaub ncaws, kev ntxuav hauv tsev kho mob thiab pej xeem. Hu rau peb tam sim no yog tias koj tab tom nrhiav tus khub lag luam txhim khu kev qha.
Lub sijhawm tshaj tawm: Lub Rau Hli-10-2021