Kev siv tshuaj tua kab mob ntawm cinnamaldehyde hauv cov khoom noj khoom haus ntim khoom

Cinnamaldehyde suav txog 85% ~ 90% ntawm cov roj tseem ceeb cinnamon, thiab Tuam Tshoj yog ib qho ntawm cov chaw cog cinnamon tseem ceeb, thiab cov khoom siv cinnamaldehyde nplua nuj. Cinnamaldehyde (C9H8O) cov qauv molecular yog ib pawg phenyl txuas nrog acrylein, nyob rau hauv lub xeev ntuj ntawm cov kua daj lossis daj daj, nrog rau qhov tshwj xeeb thiab muaj zog cinnamon thiab coke tsw, tuaj yeem siv rau hauv cov txuj lom thiab condiments. Tam sim no, muaj ntau cov ntawv ceeb toom txog kev ua haujlwm antibacterial dav dav ntawm cinnamaldehyde thiab nws cov txheej txheem, thiab cov kev tshawb fawb tau qhia tias cinnamaldehyde muaj cov nyhuv antibacterial zoo rau cov kab mob thiab fungi. Hauv kev kho mob, qee qhov kev tshawb fawb tau tshuaj xyuas kev tshawb fawb ntawm cinnamaldehyde hauv cov kab mob metabolic, cov kab mob circulatory, tiv thaiv qog thiab lwm yam, thiab pom tias cinnamaldehyde muaj cov tshuaj tiv thaiv kab mob ntshav qab zib, tiv thaiv kev rog dhau, tiv thaiv qog thiab lwm yam kev ua haujlwm pharmacological. Vim nws muaj ntau yam khoom siv, cov khoom xyaw ntuj, kev nyab xeeb, tsis muaj tshuaj lom, tsw qab tshwj xeeb thiab cov nyhuv tua kab mob dav dav, nws yog cov khoom noj khoom haus ntxiv uas tau pom zoo los ntawm Tebchaws Meskas Lub Chaw Haujlwm Saib Xyuas Khoom Noj thiab Tshuaj thiab Tuam Tshoj. Txawm hais tias qhov ntau tshaj plaws tsis txwv rau kev siv, nws qhov volatility thiab pungent tsw txwv nws daim ntawv thov dav hauv zaub mov. Kev kho cinnamaldehyde hauv zaj duab xis ntim zaub mov tuaj yeem txhim kho nws cov txiaj ntsig tua kab mob thiab txo nws cov kev cuam tshuam rau zaub mov, thiab ua lub luag haujlwm hauv kev txhim kho qhov zoo ntawm kev khaws cia zaub mov thiab kev thauj mus los thiab txuas ntxiv lub neej txee.

1. Cov tshuaj tua kab mob sib xyaw ua ke

Feem ntau ntawm cov kev tshawb fawb txog cov yeeb yaj kiab ntim khoom noj uas siv cov tshuaj ntuj thiab cov khoom uas lwj tau ua cov zaj duab xis matrix, thiab cov zaj duab xis ntim khoom noj yog npaj los ntawm kev txheej, casting lossis kev kub siab extrusion. Vim yog hom kev ua haujlwm sib txawv thiab kev sib haum xeeb ntawm cov khoom sib txawv ntawm cov membrane substrates thiab cov khoom nquag, cov yam ntxwv ntawm cov membrane tiav lawm yog txawv, yog li nws tseem ceeb heev rau kev xaiv cov membrane substrate tsim nyog. Cov khoom siv feem ntau siv rau cov yeeb yaj kiab-tsim cov khoom siv biodegradable xws li polyvinyl cawv thiab polypropylene, cov khoom ntuj xws li polysaccharides thiab cov protein, thiab cov khoom sib xyaw. Polyvinyl cawv (PVA) yog cov polymer linear, uas feem ntau tsim cov qauv network peb-seem thaum crosslinked, thiab muaj cov khoom siv kho tshuab zoo heev thiab cov khoom thaiv. Cov peev txheej matrix zoo li membrane ntuj muaj ntau thiab dav dav. Piv txwv li, polylactic acid tuaj yeem fermented los ntawm cov khoom siv raw xws li hmoov txhuv nplej siab thiab pob kws, uas muaj cov peev txheej txaus thiab rov ua dua tshiab, biodegradability zoo thiab biocompatibility, thiab yog cov khoom ntim khoom zoo tagnrho rau ib puag ncig. Cov matrix sib xyaw feem ntau yog tsim los ntawm ob lossis ntau dua membrane matrices, uas tuaj yeem ua lub luag haujlwm sib txuas piv rau ib qho membrane matrix.

Cov khoom siv kho tshuab thiab cov khoom thaiv yog cov cim qhia tseem ceeb los ntsuas qhov haum ntawm cov zaj duab xis ntim khoom. Kev ntxiv cinnamaldehyde yuav hla-txuas nrog cov polymer membrane matrix thiab yog li txo qhov molecular fluidity, qhov txo qis ntawm elongation thaum tawg yog vim qhov tsis sib xws ntawm polysaccharide network qauv, thiab qhov nce ntawm lub zog tensile yog vim qhov nce ntawm hydrophilic pawg thaum lub sijhawm tsim zaj duab xis los ntawm kev ntxiv cinnamaldehyde. Tsis tas li ntawd, cov pa roj permeability ntawm cinnamaldehyde composite membrane feem ntau tau nce, uas tej zaum yuav yog vim qhov dispersion ntawm cinnamaldehyde rau hauv polymer los tsim cov pores, voids thiab channels, txo qhov loj hloov tsis kam ntawm cov dej molecules, thiab thaum kawg ua rau muaj kev nce ntawm cov pa roj permeability ntawm cinnamaldehyde composite membrane. Cov khoom siv kho tshuab thiab permeability ntawm ntau cov composite membranes zoo sib xws, tab sis cov qauv thiab cov khoom ntawm cov polymer substrates sib txawv yog txawv, thiab kev sib cuam tshuam sib txawv nrog cinnamaldehyde yuav cuam tshuam rau kev ua tau zoo ntawm cov zaj duab xis ntim khoom, thiab tom qab ntawd cuam tshuam rau nws daim ntawv thov, yog li nws yog ib qho tseem ceeb heev rau xaiv cov polymer substrate thiab concentration tsim nyog.

Qhov thib ob, cinnamaldehyde thiab ntim zaj duab xis khi txoj kev

Txawm li cas los xij, cinnamaldehyde yog me ntsis soluble hauv dej nrog ib tug solubility ntawm tsuas yog 1.4 mg / mL. Txawm hais tias lub blending technology yog yooj yim thiab yooj yim, ob theem ntawm cov rog-soluble cinnamaldehyde thiab dej-soluble membrane matrix yog tsis ruaj khov, thiab qhov kub thiab txias siab thiab siab siab tej yam kev mob feem ntau yuav tsum tau nyob rau hauv zaj duab xis txoj kev tsim cov txheej txheem tseem ceeb txo qhov concentration ntawm muaj cinnamaldehyde nyob rau hauv lub membrane. Nws yog ib qho nyuaj rau ua tiav qhov zoo tagnrho bacteriostatic nyhuv. Embedding technology yog cov txheej txheem ntawm kev siv cov khoom siv phab ntsa los qhwv lossis adsorb cov khoom nquag uas yuav tsum tau embedded los muab kev txhawb nqa kev ua tau zoo lossis kev tiv thaiv tshuaj. Kev siv ntawm embedding technology los kho cinnamaldehyde nyob rau hauv cov ntaub ntawv ntim khoom tuaj yeem ua rau nws qeeb tso tawm, txhim kho qhov ceev khaws cia, ntev lub antibacterial laus ntawm zaj duab xis, thiab optimize cov khoom siv kho tshuab ntawm lub ntim zaj duab xis. Tam sim no, cov cab kuj siv txoj kev tsim kho ntawm kev sib txuas cinnamaldehyde nrog ntim zaj duab xis tuaj yeem muab faib ua ob pawg: dag cab kuj tsim kho thiab ntuj cab kuj tsim kho, suav nrog polymer embedding, nano liposome embedding, cyclodextrin embedding, nano av nplaum khi lossis loading. Los ntawm kev sib xyaw ua ke ntawm txheej sib dhos thiab electrospinning, cinnamaldehyde xa khoom tuaj yeem ua kom zoo dua, thiab hom kev ua thiab daim ntawv thov ntawm cinnamaldehyde tuaj yeem txhim kho.

Daim ntawv thov ntawm cinnamon aldehyde cov khoom noj khoom haus ntim zaj duab xis

Cov khoom noj sib txawv muaj cov dej sib txawv, cov khoom noj muaj pes tsawg leeg thiab cov xwm txheej khaws cia thiab kev thauj mus los, thiab kev loj hlob ntawm cov kab mob uas ua rau puas tsuaj yog qhov sib txawv heev. Cov txiaj ntsig ntawm kev khaws cia ntawm cinnamaldehyde antibacterial ntim rau cov khoom noj sib txawv kuj sib txawv.

1. Cov nyhuv tshiab rau zaub thiab txiv hmab txiv ntoo

Tuam Tshoj muaj ntau yam khoom siv ntuj tsim, uas yog cov khoom noj thiab kev ua lag luam ntawm cov zaub thiab txiv hmab txiv ntoo loj heev. Txawm li cas los xij, cov dej noo thiab qab zib ntawm cov zaub thiab txiv hmab txiv ntoo yog siab, nplua nuj nyob rau hauv cov as-ham, thiab yooj yim rau microbial kuab paug thiab puas tsuaj thaum lub sijhawm khaws cia, kev thauj mus los thiab kev muag khoom. Tam sim no, kev siv cov zaj duab xis ntim tshuaj tua kab mob yog ib txoj hauv kev tseem ceeb los txhim kho qhov zoo ntawm kev khaws cia thiab kev thauj mus los ntawm cov zaub thiab txiv hmab txiv ntoo thiab ntev lawv lub neej txee. Cov zaj duab xis cinnamaldehyde-polylactic acid composite ntawm cov txiv apples tuaj yeem txo qhov poob ntawm cov as-ham, inhibit kev loj hlob ntawm rhizopus, thiab ntev lub sijhawm khaws cia ntawm cov txiv apples mus rau 16 hnub. Thaum cinnamaldehyde active zaub mov ntim zaj duab xis tau siv rau cov ntim carrot tshiab-txiav, kev loj hlob ntawm pwm thiab poov xab tau inhibited, qhov ceev ntawm cov zaub tau txo qis, thiab lub neej txee tau ntev mus rau 12d.

2. Cov txiaj ntsig ntawm cov khoom noj nqaij kom tshiab Cov khoom noj nqaij muaj ntau cov protein, rog thiab lwm yam khoom, nplua nuj nyob rau hauv cov khoom noj khoom haus thiab saj tshwj xeeb. Thaum sov chav, kev tsim cov kab mob me me ua rau cov protein nqaij, carbohydrates thiab rog lwj, ua rau cov nqaij lwj, nplaum, xim tsaus, poob elasticity, thiab tsw tsis zoo. Cinnamaldehyde cov khoom noj khoom haus ntim zaj duab xis yog siv dav hauv cov nqaij npuas thiab ntses ntim, feem ntau inhibits kev loj hlob ntawm Staphylococcus aureus, Escherichia coli, aeromonas, poov xab, lactic acid bacteria thiab lwm yam kab mob, thiab tuaj yeem ntev lub txee lub neej ntawm 8 ~ 14d.

3. Cov txiaj ntsig ntawm cov khoom noj mis nyuj uas khaws cia tshiab Tam sim no, kev noj cov khoom noj mis nyuj hauv Suav teb nce ntxiv txhua xyoo. Cheese yog cov khoom noj mis nyuj uas muaj txiaj ntsig zoo rau kev noj haus thiab cov protein. Tab sis cheese muaj lub txee luv luv, thiab qhov pov tseg ntawm qhov kub qis tseem ceeb heev. Kev siv cov yeeb yaj kiab ntim khoom noj cinnamic aldehyde tuaj yeem ua rau lub txee ntev dua ntawm cheese, xyuas kom saj zoo ntawm cheese, thiab tiv thaiv kev puas tsuaj ntawm cheese. Rau cov cheese slices thiab cheese sauces, lub txee ntev mus txog 45 hnub thiab 26 hnub tom qab siv cinnamaldehyde active packaging, uas yog qhov zoo rau kev txuag cov peev txheej.

4. Cov khoom noj uas muaj hmoov txhuv nplej siab thiab ncuav mog qab zib yog cov khoom noj uas muaj hmoov txhuv nplej siab, ua los ntawm cov hmoov nplej ua los ntawm cov paj rwb mos mos, qab zib thiab qab heev. Txawm li cas los xij, cov mov ci thiab ncuav mog qab zib muaj lub sijhawm luv luv thiab yooj yim rau kev kis kab mob pwm thaum muag, ua rau cov khoom noj puas tsuaj thiab pov tseg. Kev siv cov khoom ntim khoom noj uas muaj cinnamaldehyde hauv cov ncuav mog qab zib thiab cov mov ci hlais tuaj yeem tiv thaiv kev loj hlob thiab kev nthuav dav ntawm penicillium thiab pwm dub, thiab txuas lub sijhawm txee mus txog 10 ~ 27d, raws li.

 

Cinnamaldehyde muaj qhov zoo ntawm qhov chaw muaj ntau, bacteriostasis siab thiab tsis muaj tshuaj lom. Raws li tus neeg sawv cev bacteriostasis hauv cov khoom noj khoom haus, qhov ruaj khov thiab qeeb tso tawm ntawm cinnamaldehyde tuaj yeem txhim kho los ntawm kev tsim thiab ua kom zoo dua ntawm tus neeg xa khoom, uas yog qhov tseem ceeb heev rau kev txhim kho qhov zoo ntawm kev khaws cia thiab kev thauj mus los ntawm cov khoom noj tshiab thiab txuas ntxiv lub neej txee ntawm cov khoom noj. Nyob rau hauv xyoo tas los no, cinnamaldehyde tau ua ntau yam kev ua tiav thiab kev nce qib hauv kev tshawb fawb ntawm kev khaws cia cov khoom noj khoom haus, tab sis kev tshawb fawb txog daim ntawv thov tseem nyob rau theem pib, thiab tseem muaj qee qhov teeb meem yuav tsum tau daws. Los ntawm kev kawm sib piv ntawm cov teebmeem ntawm cov neeg xa khoom sib txawv ntawm cov khoom siv kho tshuab thiab cov khoom thaiv ntawm daim nyias nyias, kev tshawb nrhiav tob tob ntawm hom kev ua haujlwm ntawm cinnamaldehyde thiab tus neeg nqa khoom thiab nws cov kinetics tso tawm hauv ntau qhov chaw, kev kawm txog kev cuam tshuam ntawm txoj cai loj hlob ntawm cov kab mob me me hauv cov khoom noj khoom haus ntawm kev puas tsuaj ntawm cov khoom noj khoom haus, thiab cov txheej txheem tswj hwm ntawm cov khoom ntim antibacterial ntawm lub sijhawm thiab tso tawm ntawm cov neeg sawv cev antimicrobial. Tsim thiab tsim cov txheej txheem ntim khoom uas tuaj yeem ua tau raws li cov kev xav tau khaws cia khoom noj sib txawv.